Join Us



We are always looking for new talent to strengthen our team. We are an interdisciplinary and international team jointly hosted at German Cancer Research Center (DKFZ) and European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany.

Below you can find information about current opportunities. Additionally, we encourage interested candidates to reach out with a project proposal to explore funding opportunities.


To apply for a postdoctoral position in our group, please refer to the DKFZ Postdoctoral Fellowship and EMBL Postdoctoral Programme.

To apply for a PhD position in our group, please refer to the EMBL International PhD Programme and the DKFZ International PhD Programme.

Additionally, we regularly participate in the ELLIS PhD & Postdoc Programme Call.


Please also refer to the DKFZ and EMBL job offers.



Unsolicited Application:

If you do not apply through one of the specific openings mentioned above, please send a CV, a letter of motivation and ideally 2 references in a single pdf directly to o.stegle [at] dkfz.de and put kevin.domanegg [at] dkfz-heidelberg.de in cc. Successful letter of interest should be tailored to our group, mentioning projects or articles of our group that you find interesting, and explaining how you would fit in our group. Additional supporting documents demonstrating your prior experience incl. code samples of previous projects and links to a GitHub repository are very welcome.

Current research themes in our group include:
A) Computational Genetics: We develop statistical and machine-learning methods to dissect often overlooked dimensions of the genotype-phenotype relationship, including genetic effects of rare variants and indirect genetic effects.
B) Spatial and Multi-Omics: We develop foundational methods to integrate high-dimensional molecular profiles assayed in bulk or at the single-cell level. This includes innovations to allow for integrating multi-omics readouts across time and space, as well as methods for spatial omics technologies.
C) Causal Inference Models: We develop methods to model genetic perturbation effects and infer causality. We leverage opportunities provided by engineered perturbations using CRISPR screens combined with a single-cell readout.

We are pleased to offer opportunities for your BSc or MSc thesis or an internship in our lab. If you are interested, please contact us with a CV and a motivation letter tailored to our lab interests.


Like most people these days we get far too much email. Because of this we sometimes miss important messages. Please accept our apologies if we don’t respond to you in a timely manner, and feel free to resend your message.